1. Introduction
A female patient who sought treatment at SLNS Nature Cure Hospital, presented with multiple health concerns, including migraines, insomnia, shivering, panic attacks, and hypertension. These conditions severely impacted her physical and mental well-being, causing significant distress. Seeking relief, Daljit opted for a holistic treatment approach that incorporated natural therapies, along with a well-structured, balanced diet. Over the course of her treatment, significant improvements were observed in her physical and mental health, supported by reductions in key metabolic indicators such as insulin resistance, blood glucose, and body weight.
2. Patient Information
Daljit Kaur had a medical history of migraines, hypertension, panic attacks, and insomnia. She also reported experiencing frequent episodes of shivering and general physical discomfort, which affected her daily activities. The psychological toll of her physical ailments, including high stress levels, exacerbated her condition. Daljit had a body weight of 75.2 kg and was on medication for several conditions. She sought a holistic and natural treatment plan to address both her physical symptoms and emotional well-being.
3. Medication History
Daljit’s medication history involved multiple prescriptions to manage her symptoms. The following table summarizes her medication regimen and the adjustments made during her treatment.
| S.No | Medication | After Treatment | Mechanism |
| 1 | Lemborexant (T-DAYVIGO) 10 mg | Tapered to 5 mg | Dual orexin receptor antagonist, induces sleep by blocking wakefulness-promoting orexin receptors. |
| 2 | Naproxen (T ZONTOPAN) 500 mg | Tapered | Nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX enzymes to reduce inflammation and pain. |
| 3 | Domperidone (T. NAPRAD) 10 mg | Tapered | Dopamine antagonist that helps reduce nausea and vomiting. |
| 4 | Vortioxetine (T VORMINID OD) 20 mg | Reduced to 10 mg | Serotonin modulator and stimulator that improves mood and cognitive function. |
| 5 | Clonazepam (T. MELZAP MD) 0.25 mg | Tapered | Benzodiazepine that reduces anxiety and prevents seizures by enhancing GABA effects. |
| 6 | Propranolol hydrochloride (T MIGRABETA T R) 40 mg and 80 mg | Reduced to 40 mg | Beta-blocker that reduces blood pressure and alleviates migraine symptoms. |
| 7 | Loperamide (T TOPAZ OD) 50 mg | Tapered | Anti-diarrheal that works by slowing intestinal motility. |
| 8 | Gabapentin (T ADGABA) 100 mg | Reduced to 50 mg | Anticonvulsant that prevents seizures by inhibiting excitatory neurotransmitter release. |
| 9 | Nortriptyline hydrochloride 300 mg | Reduced to 150 mg | Tricyclic antidepressant that increases serotonin and norepinephrine levels. |
Lemborexant , initially prescribed at 10 mg, was tapered to 5 mg. This dual orexin receptor antagonist induces sleep by blocking wakefulness-promoting orexin receptors. Naproxen, a nonsteroidal anti-inflammatory drug at 500 mg, was tapered to reduce inflammation and pain by inhibiting COX enzymes. Domperidone, initially at 10 mg, was tapered to reduce nausea and vomiting by acting as a dopamine antagonist. Vortioxetine, a serotonin modulator, was reduced from 20 mg to 10 mg, helping to improve mood and cognitive function. Clonazepam, at 0.25 mg, was tapered to reduce anxiety and prevent seizures by enhancing GABA effects. Propranolol hydrochloride, initially prescribed at 40 mg and 80 mg, was reduced to 40 mg to alleviate migraine symptoms and lower blood pressure as a beta-blocker. Loperamide, originally at 50 mg, was tapered to slow intestinal motility as an anti-diarrheal. Gabapentin, initially prescribed at 100 mg, was reduced to 50 mg as an anticonvulsant to prevent seizures by inhibiting excitatory neurotransmitter release. Lastly, Nortriptyline hydrochloride, initially prescribed at 300 mg, was reduced to 150 mg to increase serotonin and norepinephrine levels as a tricyclic antidepressant.
4. Naturopathic and Lifestyle Interventions
Daljit’s treatment plan incorporated both conventional and natural therapies:
- Dietary Modifications: A balanced, anti-inflammatory diet was introduced, focusing on weight loss, improved glucose metabolism, and cardiovascular health.
- Natural Therapies: Yoga, meditation, and herbal treatments were integrated into the treatment plan to help manage stress, improve mental health, and promote overall well-being.
- Medication Adjustments: The tapering of her pharmaceutical medications was done gradually to reduce dependency on drugs and minimize potential side effects.
- Holistic Health Counseling: Addressing mental health concerns through counseling, stress management techniques, and relaxation methods.
5. Results and Follow-Up
| S.No | Biomarker | Before treatment | After Treatment |
| 1 | Homa-IR | 2.10 | 1.67 |
| 2 | HbA1c | 5.9% | 5.3% |
| 3 | Magnesium | 1.87 | 2.13 |
| 4 | Hs CRP | 13.99 | 6.3 |
| 5 | eGFR | 78 | 86 |
| 6 | Body Weight | 75.2 kg | 69.5 kg |
| 7 | Blood Glucose Levels | 123 mg/dL | 105 mg/dL |
| 8 | Blood Pressure | 150/100 | 120/80 |
| 9 | Migraine Frequency | Frequent | Reduced |
| 10 | Panic Attacks | Frequent | Reduced |
HOMA-IR, which measures insulin resistance, decreased from 2.10 to 1.67, indicating improved insulin sensitivity. HbA1c, a marker of long-term blood sugar control, reduced from 5.9% to 5.3%. Her body weight dropped from 75.2 kg to 69.5 kg, contributing to overall better health. Blood glucose levels improved, decreasing from 123 mg/dL to 105 mg/dL. Blood pressure readings showed a marked improvement, from 150/100 mmHg to 120/80 mmHg. initial magnesium level of 1.87, which improved to 2.13 after proper supplementation. This change directly contributed to a significant reduction in inflammatory markers, as reflected in the drop in Hs-CRP levels from 13.99 to 6.3. Lower Hs-CRP indicates reduced inflammation, which can alleviate common hypothyroid symptoms like fatigue, joint pain, and brain fog. The frequency of migraines and panic attacks also reduced significantly, with Daljit experiencing fewer episodes. These changes reflect the success of the holistic treatment plan in improving Daljit’s physical and mental health.
6. Discussion
Daljit’s treatment involved a well-coordinated plan combining both conventional medications and naturopathic treatments. The gradual reduction of pharmaceutical drugs and the integration of lifestyle changes and holistic therapies led to significant improvements in her symptoms. Notably, key biomarkers such as insulin resistance, HbA1c, blood glucose levels, and body weight showed marked improvement. Additionally, there was a substantial reduction in the frequency of migraines, panic attacks, and general anxiety.
7. Conclusion
Daljit’s case underscores the efficacy of a holistic treatment approach in managing complex health conditions. The combined use of naturopathic interventions, lifestyle modifications, and careful tapering of medications led to significant improvements in both her physical and mental health. Migraines have shown reduced frequency and severity with ongoing management through natural therapies. Insomnia has improved significantly, with better sleep quality and a decreased reliance on sedative medications. Episodes of shivering and panic attacks have substantially decreased, effectively managed through stress reduction techniques and lifestyle changes. Additionally, hypertension has been brought under control, with normalized blood pressure readings, reducing the dependency on antihypertensive medications. Daljit’s case demonstrates the potential of integrative medicine in addressing both the physical and psychological aspects of complex health conditions.
