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Battling Lupus and RA Since Childhood

1.Introduction:

Ms. XXX , a 32-year-old Russian translator from Uttarakhand, has been on a long and challenging medical journey marked by the dual diagnosis of Systemic Lupus Erythematosus (SLE) and Rheumatoid arthritis (RA). Her health struggles began as early as age 10 with recurrent infections which gradually worsened leading to severe fatigue, joint stiffness, gastrointestinal issues, and emotional distress. Diagnosed at 17 with autoimmune disorders, she cycled through various treatments—from immunosuppressants and corticosteroids to herbal remedies and physiotherapy. She faced multiple complications including anemia, disc bulge, skin discoloration, dry mouth, hair thinning, and latent tuberculosis, all of which significantly impacted her physical and mental well-being. The financial and emotional toll of the disease further deepened following the loss of her father, leading to panic attacks and suicidal ideation. After years of fluctuating health, she found relief through an integrative treatment approach that combined Allopathy, Ayurveda, and Naturopathy, especially at SLNS Nature Cure Hospital. Here, a tailored regimen involving Anti-inflammatory diets, Detox therapies, Yoga, Supplements, and Herbal medicines helped stabilize her symptoms and improved her overall quality of life. Her case underscores the importance of personalized, holistic care in managing complex autoimmune conditions.

2.Patient Information:

NAME: XXX

GENDER:Female

AGE: 32

A 32-year-old unmarried female, Russian translator from Uttarakhand, has faced a long and complex battle with autoimmune diseases, primarily Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis(RA), which began affecting her health from the age of 10. Initially marked by recurrent infections, tonsillitis, and mouth ulcers, her symptoms gradually escalated to chronic dry mouth, debilitating joint pain, fevers, and gastrointestinal issues. Diagnosed formally at the age of 17 at AIIMS with SLE and Rheumatoid Arthritis, she has began immunosuppressive therapy with Mycophenolate mofetil and Corticosteroids. However, prolonged use of medications like Wysolone led to side effects including hyperpigmentation, hair thinning, and fluctuating weight. Her health further declined due to severe anemia (hemoglobin as low as 5 g/dL), elevated ESR (113 mm/hr), and complications such as a disc bulge in 2021 and latent tuberculosis. She sought alternative care at Chaudhary Brahm Prakash Ayurveda Charak Sansthan and later pursued naturopathy at Prakruti Shakti in 2024, incorporating anti-inflammatory diets, yoga, detox therapies, and herbs like Nelausiri and Triphala. During her stay at SLNS Nature Cure Hospital, a holistic plan was implemented, focusing on dietary correction, physiotherapy, and emotional healing through mindfulness and relaxation. By integrating traditional Ayurvedic and modern naturopathic methods with allopathic care, she experienced stabilization in her health. In 2025, she returned to SLNS Hospital for a 22-day follow-up stay, reporting symptoms including persistent fatigue, indigestion, bloating, constipation, dizziness (ongoing for 4 months), recurring headaches, and musculoskeletal pain—especially in the knees (2 weeks) and back (since 2021). A comprehensive re-evaluation reaffirmed the chronic nature of her autoimmune condition, while also revealing gastrointestinal dysfunction likely influenced by prolonged medication use and Stress. Her current management includes continued use of supplements (Vitamin D, B12, Omega-3s, probiotics), therapeutic massages, hydrotherapy, yoga, herbal teas, and detox regimens to further alleviate inflammation and improve digestion and energy levels. Despite the persistent nature of SLE, Kiran’s case illustrates the resilience possible through integrative care and a personalized, holistic treatment plan.

3.Medication History:
S.NOMEDICATIONAFTER TREATMENTMECHANISM
1Tacrolimus 0.5mg 1-0-1 ContinuedA immunosuppressant commonly used to prevent organ rejection in transplant patients and manage autoimmune conditions.
2Prednisolone 2.5mg1-0-1  TaperedA corticosteroid that reduces inflammation and suppresses immune responses. It inhibits phospholipase A2, lowering prostaglandins and cytokines to control autoimmune and allergic conditions.
3Hydroxychloroquine sulphate 200mg0-0-1ContinuedIt is antimalarial and immunomodulatory drug. It increases lysosomal pH in immune cells, inhibiting antigen processing and cytokine release, reducing inflammation in autoimmune diseases like rheumatoid arthritis and lupus.

She takes Tacrolimus 0.5 mg (1-0-1), an immunosuppressant that inhibits T-cell activation to control autoimmune responses. It helps manage conditions like SLE and Rheumatoid Arthritis by reducing immune overactivity. Prednisolone 2.5 mg (1-0-1) was tapered, which suppresses inflammation by blocking phospholipase A2, lowering cytokine and prostaglandin levels. It’s used to manage chronic inflammation in autoimmune diseases. Hydroxychloroquine Sulphate 200 mg (0-0-1) is an antimalarial with immunomodulatory effects, raising lysosomal pH to block antigen processing. It reduces flare-ups and inflammation in lupus and rheumatoid arthritis.

4.Naturopathy And Lifestyle Intervention:

Lifestyle Modification: Practiced sun protection, mindfulness, regular rest, and hydration to manage lupus symptoms and improve overall well-being.

Diet Changes: She adopted an anti-inflammatory, nutrient-rich diet with probiotics to support immunity, ease anemia, and enhance digestion.

Yogic Intervention: Gentle yoga and breathing exercises helped reduce stiffness, improve flexibility, and relieve headaches and anxiety.

Massage & Hydrotherapy Treatments: Therapeutic massages and hydrotherapy alleviated pain, improved circulation, and reduced inflammation.

5.Results And Follow Up:
S.NOBIOMARKERSBEFORE TREATMENTAFTER TREATMENT
1.RBC4.634.84
2VITAMIN D30.5557.42
3ESTRADIOL11256
4VITAMIN B10.491.98
5SGOT/SGPT RATIO4.243.38
6SERUM GLOBULIN4.063.61
7PROTEIN8.297.68
8PH6.55.5
9SPECIFIC GRAVITY1.0051.015

Her latest test results reflect encouraging improvements across several markers, supporting her recovery from SLE and related symptoms. Her RBC count improved from 4.63 to 4.84, aiding better oxygen delivery and reducing fatigue. Vitamin D levels rose from 30.55 to 57.42, helping modulate immune function and easing joint pain. Estradiol levels dropped from 112 to 56, contributing to hormonal balance and reduced inflammation. Vitamin B1 significantly increased from 0.49 to 1.98, improving nerve health and relieving dizziness. A decreased SGOT/SGPT ratio from 4.24 to 3.38 indicates better liver function and reduced medication load. Serum globulin decreased from 4.06 to 3.61, reflecting a reduction in systemic inflammation. Total protein levels dropped slightly from 8.29 to 7.68, balancing nutrient status and improves immunity. Her urine pH decreased from 6.5 to 5.5, supporting detoxification and microbial balance, while the rise in specific gravity from 1.005 to 1.015 indicates improved hydration and kidney concentration function. These changes collectively mark progress in her overall vitality and immune regulation.

EULAR SCALE:

CriteriaBefore TreatmentAfter Treatment
Clinical Domains
leukopeniaLower levels of WBC – 3Lower levels of WBC – 3
Mucocutaneous changesAlopecia 2, Oral ulcers 2, Acute cutaneous lupus 6, scored 10Alopecia- 2, Oral ulcers 2, and No acute cutaneous lupus, scored 4
FeverIntermittent fever, scored 2No fever symptoms, scored 0
Joint InvolvementJoint pain/Swelling, scored 6Joint pain/Swelling, scored 0
Total Clinical Domain Score217
Immunological Domains
Presence of Anti-nuclear antibodyContributing 6 to the immunological scoreContributing 6 to the immunological score
Total Immunological Score66
Overall EULAR Score2713

SYMPTOM TRACKER

SYMPTOMS SCORE (0-5)BEFORE TREATMENTSCORE (0-)AFTER TREATMENT
HEADACHE50
DARK CIRCLES33
POOR VISION44
NASAL BLEEDING22
VOMITING                 4
INDIGESTION42
STOMACH CRAMPS32
ANXIETY43
NERVOUSNESS4.5
RESTLESSNESS42
ARTHRITIS40
WEAKNESS32
TOTAL44.5 23
6.Discussion:

From recurring infections and joint pain to anemia, dry mouth, and skin issues, her condition progressively worsened, despite allopathic interventions with steroids and immunosuppressants. The side effects of long-term medication use and the emotional trauma of losing her father added to her burden, triggering anxiety, panic attacks, and suicidal thoughts. In search of a more sustainable path, Kiran turned to integrative care at SLNS Nature Cure Hospital Referred by Dr. Cizith from Pune, where a blend of anti-inflammatory diets, herbal supplements, yoga, detox therapies, and emotional healing techniques offered a turning point. Over time, she experienced relief from many chronic symptoms, improved energy levels, reduced inflammation, and better hormonal and liver function. Her symptom scores dropped significantly, joint pain and headaches subsided, and her EULAR disease activity score improved remarkably. While some concerns like poor vision and dark circles remain, Kiran’s case is a compelling testament to the power of personalized, holistic care in stabilizing complex autoimmune conditions and restoring quality of life.

7.Conclusion:

Her journey from chronic suffering to gradual stability exemplifies the transformative power of integrative healing, particularly through her treatment at SLNS Nature Cure Hospital. Once burdened with a range of debilitating symptoms—Joint pain, Recurrent headaches, Vomiting, Indigestion, Severe fatigue, Anxiety, and Dizziness—she saw remarkable relief after adopting naturopathic therapies tailored to her autoimmune condition. Her EULAR score reduced significantly from 27 to 13, with key improvements such as the complete resolution of joint pain and fever, and partial relief from mucocutaneous symptoms. Her headaches, vomiting, and arthritis pain completely subsided, and symptoms like indigestion, nervousness, and weakness reduced substantially. Blood biomarkers supported this clinical progress, showing better oxygenation (RBC rose to 4.84), improved vitamin D (57.42) and B1 (1.98) levels, balanced hormones (estradiol dropped to 56), and lower inflammation markers like SGOT/SGPT ratio and serum globulin. While issues like poor vision and dark circles remain, her overall symptom score dropped from 44.5 to 23, highlighting the tangible benefits of SLNS’s holistic regimen—combining detox therapies, yoga, personalized diet, and emotional healing. Her story reflects not only a reduction in clinical severity but also a regained sense of strength and hope, affirming that chronic autoimmune conditions can be managed and eased with consistent, integrative care.