1.Introduction:
Amrutha Siri, a 27-year-old woman, has faced ongoing health challenges due to Polycystic Ovary Syndrome (PCOS) for five years. Initially dealing with irregular menstrual cycles and hormonal imbalances, she experienced a period of relief three years ago when her symptoms reversed. However, her PCOS symptoms resurfaced, causing significant distress. In addition to her reproductive health issues, Amrutha developed knee pain and irritable bowel syndrome (IBS) over the past two years, further complicating her daily life. Seeking comprehensive care, she visited SLNS Hospital in hopes of finding an effective treatment plan to manage her symptoms and restore her well-being.
2.Patient Information:
Name: Amrutha Siri
Age: 27 years
Gender: Female
Amrutha Siri, a 27-year-old woman, arrived at SLNS Hospital seeking relief from a challenging set of health issues. For five years, she had been grappling with Polycystic Ovary Syndrome, which significantly disrupted her life. Her menstrual cycles were irregular, lasting between 36 to 40 days, with a flow duration of 4 to 6 days.
Three years ago, Amrutha experienced a remarkable reversal of her PCOD symptoms, bringing her much-needed respite. However, her symptoms returned, causing her significant distress. Adding to her challenges, Amrutha developed knee pain and irritable bowel syndrome two years ago, further complicating her daily life and making it difficult for her to maintain her usual active lifestyle. Desperate for a solution, she turned to SLNS Hospital, hoping for a comprehensive treatment plan to restore her health and bring her life back on track.
3.Naturopathic And Lifestyle Intervention:
Anti-Inflammatory Diet: Focused on omega-3 fatty acids, antioxidants, and low-glycemic-index foods to regulate blood sugar, reduce inflammation, and support hormonal balance.
Hormone-Regulating Foods: Included flaxseeds, turmeric, and ginger to manage PCOS-related symptoms.
Dietary Adjustments: Avoided processed foods, refined sugars, and dairy to alleviate IBS symptoms and reduce inflammation.
Gentle Exercises: Incorporated yoga, swimming, or walking to improve circulation, reduce knee pain, and enhance joint flexibility.
Stress Management: Practiced mindfulness meditation, deep breathing exercises, and journaling to balance cortisol levels and support hormonal health.
Hydration and Sleep: Ensured adequate hydration and maintained a regular sleep schedule to manage symptoms and boost energy.
4.Results And Follow Ups:
| S.NO | BIOMARKER | DAY 1 | DAY 20 |
| 1 | LH | 7.9 | 9.01 |
| 2 | PROLACTIN | 52.9 | 18.7 |
| 3 | FREE ANDROGEN INDEX | 9.7 | 4.29 |
| 4 | FREE TESTOSTERONE | 2.23 | 1.73 |
| 5 | TESTOSTERONE | 59.6 | 56.2 |
| 6 | AMH (ANTI MULLERIAN HORMONE) | 6.37 | 11.87 |
| 7 | DHEA-S | 161 | 170.8 |
| 8 | FSH | 3.37 | 2.94 |
| 9 | E2 (ESTRADIOL) | 79 | 204 |
| 10 | SHBG (SEX HORMONE BINDING GLOBULIN) | 21.3 | 45.4 |
| 11 | FASTING INSULIN | 20.68 | 5.19 |
| 12 | HOMA IR | 4.81 | 1.05 |
The analysis of hormonal parameters before and after treatment reveals significant progress in managing the patient’s health issues. Initially, on June 1, 2024, during the ovulation phase, the patient’s LH was 7.9, below the normal range of 8.7-76.3. By July 5, 2024, in the luteal phase, LH had increased to 9.01, which, while still within the normal range of 0.5-16.9, indicates a positive progression. LH is crucial for triggering ovulation, and this increase reflects an improvement in ovulatory function.
Prolactin levels were significantly high before treatment at 52.9, which can adversely affect ovarian follicles. Post-treatment, prolactin dropped to 18.7, marking a substantial improvement and indicating enhanced ovarian and pituitary function.
The Free Androgen Index decreased from 9.7 to 4.29, showcasing a great reduction in androgens. Lower androgen levels help mitigate symptoms like hirsutism and ovarian cysts. Similarly, free testosterone levels fell from 2.23 to 1.73, which further supports the reduction of hirsutism and cyst formation.
Anti-Müllerian Hormone levels raise from 6.37 to 11.87, an extraordinary improvement that suggests an increase in the number of available eggs, thus benefiting fertility in PCOS.
DHEA-S increased slightly from 161 to 170.8, which may support hormonal balance and ovulation. Follicle-Stimulating Hormone (FSH) decreased from 3.37 to 2.94, reflecting the normal shift from follicle development to corpus luteum function post-ovulation.
Estradiol (E2) levels surged from 79 to 204, an extraordinary extent indicating improved menstruation and fertility. SHBG also increased from 21.3 to 45.4, signaling enhanced hormonal balance and metabolic health.
Lastly, fasting insulin levels dropped from 20.68 to 5.19, showcasing great progress in reducing insulin resistance, a common issue in PCOS. Overall, these changes represent significant advancements in managing the patient’s hormonal health and PCOS symptoms.
Restored her digestive health, addressing issues such as bloating, acidity, and indigestion through naturopathic modalities.
5.Discussion:
Amrutha Siri’s hormonal improvements over 20 days reflect positive progress in managing her PCOS symptoms. Key changes include increased LH and estradiol, indicating better ovulatory function and menstrual health. A significant drop in prolactin and androgens, alongside a rise in AMH, suggests improved fertility potential and a reduction in symptoms like hirsutism and cyst formation. Improved insulin levels and reduced insulin resistance further support better metabolic health. Overall, the treatment has effectively balanced her hormones, reduced PCOD symptoms, and improved fertility outcomes.
6.Conclusion:
Amrutha Siri’s treatment resulted in substantial hormonal improvements, reflecting a positive shift in her PCOD management. Despite a brief period of symptom relief, her PCOD symptoms had resurfaced, leading to further distress. However, through the holistic approach at SLNS Hospital, Amrutha experienced significant improvement in all areas. Her menstrual cycles normalized, knee pain was alleviated, and her irritable bowel syndrome symptoms were drastically reduced, allowing her to regain her active lifestyle.
Amrutha’s journey to recovery stands as a testament to the power of integrated care in addressing complex, chronic health issues. With her symptoms under control, Amrutha is now able to live a healthier, more balanced life—proving that even long-standing conditions can be managed and reversed with the right treatment approach.
The decrease in androgens, prolactin, and insulin resistance, combined with increases in key hormones like LH, estradiol, and AMH, suggests better fertility potential and reduced symptoms. These changes indicate that a comprehensive approach, integrating medical and lifestyle interventions, can effectively address PCOD symptoms and promote long-term health improvements.